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Summary

Nearly thirty years ago, in 1974, the volume on Angiotensin edited by Irvine H.Page and F. Merlin Bumpus expanded the Handbook of Experimental Pharmacology. Even after two decades the multiplicity of its actions appears not to have been fully discovered. To call attention to its many functions is one of the purposes of this book. This new edition of the volume on Angiotensin attempts to provide an updated account of the knowledge and findings accumulated since the complexity of angiotensin was so accurately recognized.

Table of Contents

Part 4. Tissues
Vascular
Angiotensin II and Oxidative Stress
3(18)
N. Tsilimingas, A. Warnholtz, M. Wendt, T. Münzel
Angiotensin II and Atherosclerosis
21(18)
H. Drexler, B. Schieffer
Angiotensin II and Vascular Extracellular Matrix
39(26)
J.W. Fischer
Renin-Angiotensin Inhibitors and Vascular Effects
65(16)
E.L. Schiffrin
Brain/Nervous System
Angiotensin Pathways and Brain Function
81(20)
F. Qadri
Involvement of the Renin Angiotensin System in the Regulation of the Hypothalamic Pituitary Adrenal Axis
101(14)
G. Aguilera
Angiotensin Actions on the Brain Influencing Salt and Water Balance
115(26)
M.J. McKinley, D.A. Denton, M.L. Mathai, B.J. Oldfield, R.S. Weisinger
Angiotensin Receptor Signaling in the Brain: Ionic Currents and Neuronal Activity
141(22)
C. Sumners, E.M. Richards
Angiotensin, Neuroplasticity and Stroke
163(30)
A. Blume, J. Culman
Heart
Role of Angiotensin II in Cardiac Remodeling
193(16)
J. Diez
Pathophysiology of Cardiac AT1 and AT2 Receptors
209(28)
J. Fielitz, V. Regitz-Zagrosek
Activation of the Renin-Angiotensin System After Myocardial Infarction
237(18)
W.M. Aartsen, J.F.M. Smits, M.J.A.P. Daemen
Kidney and Adrenal Gland
Angiotensin II, the Kidney and Hypertension
255(30)
O. Grisk, R. Rettig
Angiotensin and Aldosterone Biosynthesis
285(58)
A. M. Capponi, M.E Rossier
Aldosterone: Clinical Aspects
343(16)
T.L. Goodfriend
Part 5. Inhibition of the Renin-Angiotensin System
ACE Inhibitors
Interactions Between the Renin-Angiotensin and the Kallikrein-Kinin System
359(16)
P. Wohlfart, G. Wiemer
ACE Inhibitors: Pharmacology
375(42)
P. Gohlke, B.A. Scholkens
AT1 Antagonists
AT1 Receptor Antagonists: Pharmacology
417(36)
M. de Gasparo
Clinical Pharmacology of Angiotensin II Receptor Antagonists
453(32)
M. Maillard, M. Burnier
Combined Blockade of the Renin Angiotensin System with ACE Inhibitors and AT1 Receptor Antagonists
485(34)
M. Azizi, J. Ménard
NEP/ACE Inhibitors
NEP/ACE Inhibitors: Experimental and Clinical Aspects
519(26)
R. Corti, F. Ruschitzka, T.F. Lüscher
Part 6. Clinical Qutlook
Inhibitors of the RAS: Evidence-Based Medicine
545(48)
W. Schulz
Subject Index 593

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