The New Standard for Evaluating Drugs and Herbal Interactions The most comprehensive and clinically relevant table of Cytochrome P450 enzyme substrates, inducers and inhibitors in the industry. Each interaction monograph contains the following three ratings: I. RELIABILITY RATING Indicating the quantity and nature of documentation for an interaction II. RISK RATING Indicating the type of action to be taken in response to the data A- No Known Interaction B- No Action Needed C- Monitor Therapy D- Consider Therapy Modification X- Avoid Combination III. SEVERITY RATING Indicating the reported or possible magnitude of an interaction outcome Detailed patient management suggestions Discussion of published reports and potential mechanisms Full reference citations Identifies the greatest number of potential interactions compared to any other available references User-friendly structure Over 3,000 brand names representing nearly 1,800 generic drugs Nearly 70 new drugs, incl